Insulin signal transduction pathway
Iglucosed glucosejglucosed
from Dg Iglucosedblood
glucosed stream
Pp
if secondarymessengers
iDp
phosphorylate phosphorylate phosphorylate
I
y
Phosphorylate
T
o phosphorylate phosphorylate
gig amplified
vesine bykinaseprotein
phosphorylate
mommy
phosphorylate
Qactivation of
mTORpromotes inhibition of asks
proteinsynthesis inhibition of allows for glycogenFoxoprevents
glycogenolysist synthesis
gluconeogenesis
stopsglucose
release
I